Author: Naveed Ahmad

On this tutorial, we carry out a complicated single-cell RNA-seq evaluation workflow utilizing Scanpy on the PBMC-3k benchmark dataset. We begin by loading the dataset, inspecting its construction, and making use of high quality management checks to judge gene counts, complete counts, mitochondrial content material, and ribosomal gene alerts. We then filter low-quality cells and genes, detect potential doublets with Scrublet, normalize the info, apply log transformation, and determine extremely variable genes for downstream evaluation. Additionally, we rating cell-cycle phases, regress out undesirable technical variation, scale the info, and scale back dimensionality utilizing PCA, UMAP, and t-SNE. We additionally cluster…

Amazon is including a short-form video feed to the Prime Video app known as “Clips,” the corporate announced on Friday. Rolling out first within the U.S., Clips will embody…effectively, clips of reveals on Prime Video which might be designed to hook a viewer and get them to offer the total present a strive. From that clip, customers can add a title to their watchlist, share it with a good friend, or navigate to hire, purchase, or entry the title by means of their subscription. “Clips provides prospects a complete new method to browse with quick, customized snippets tailor-made to their…

Porsche is closing three of its subsidiaries because it copes with falling gross sales and declining earnings, the German automaker introduced Friday. The automaker’s battery subsidiary, Cellforce Group, is maybe the highest-profile casualty. The division had already been by a “realignment” in August after Porsche dropped plans to make its personal batteries, turning Cellforce right into a analysis and growth arm. Now, Porsche says it’s pursuing a “technology-open powertrain technique” — corporate-speak that signifies the automaker will rely extra closely on different firms for its batteries. Porsche eBike Efficiency, which made e-bike drive methods, and Cetitec, a networking software program…

Cloudflare on Thursday joined a rising record of tech firms — together with Meta, Microsoft, and Google — which have reported elevated income alongside and large layoffs, attributing each developments to their use of AI. Cloudflare, which gives web safety and efficiency companies to hundreds of thousands of internet sites worldwide, introduced it was slicing its workforce by roughly 20%, which equates to 1,100 individuals, it stated as a part of its first quarter 2026 earnings report on Thursday. “We’ve by no means achieved one thing like this in Cloudflare’s historical past,” co-founder and CEO Matthew Prince said Thursday on…

Thinker Nick Bostrom not too long ago posted a paper, the place he postulated {that a} small likelihood of AI annihilating all people could be definitely worth the danger, as a result of superior AI may relieve humanity of “its common demise sentence.” That upbeat gamble is kind of a leap from his earlier darkish musings on AI, which made him a doomer godfather. His 2014 e book Superintelligence was an early examination of AI’s existential danger. One memorable thought experiment: An AI tasked with making paper clips winds up destroying humanity as a result of all these resource-needy individuals…

Peter Williams, a veteran cybersecurity govt who was the pinnacle of the hacking and surveillance tech division of U.S. protection contractor L3Harris, has been ordered to pay $10 million to its former employer. Williams was the central determine in one of many worst leaks of superior hacking instruments within the historical past of the US and its closest allies. On Wednesday, a judge ordered Williams to pay that quantity in restitution on high of the $1.3 million he had already been ordered to pay to L3Harris. Williams, a 39-year-old Australian citizen who beforehand labored in one in every of Australia’s…

Billionaire California gubernatorial candidate Tom Steyer is rolling out a brand new proposal that may assure jobs with advantages for staff displaced by synthetic intelligence. He’s the primary state-wide candidate to make such a pledge.The plan, which builds on a broader AI coverage framework Steyer released in March, guarantees to make California “the primary main economic system on the planet” to make sure “good-paying” jobs to staff impacted by AI. To take action, Steyer tells WIRED he plans to construct off a earlier proposal to introduce a “token tax” which might tax large tech firms “a fraction of a cent…

Sweden-based caller ID firm Truecaller stated it should reduce 70 jobs, or roughly 15% of its workforce, within the second quarter, as the corporate posted its Q1 2026 outcomes with a decline in income and earnings. Truecaller blamed real-money gaming in India, modifications in promoting companion algorithms, and battle within the Center East for the slide. As TechCrunch reported final month, the corporate is already going through challenges from India’s telecom-led options, resembling Calling Name Presentation (CNAP) identification service, and 5% year-on-year decline in downloads final yr. In its Q1 2026 outcomes, Truecaller’s internet gross sales dropped 27% to 362 million…

After years of hints and preparation, the Uber-backed electrical bike and scooter rental startup Lime has filed for an preliminary public providing. The corporate, which is integrated as Neutron Holdings Inc., has eyed the general public markets for a minimum of 5 years. CEO Wayne Ting final spoke instructed TechCrunch in 2023 concerning the prospect of an IPO, noting on the time that Lime had the the economics, the expansion, and the profitability to take the startup public. All that was required was correct market situations. That day has apparently arrived. The corporate intends to checklist on ​Nasdaq beneath the…

Whereas AI disruption looms over many legacy SaaS corporations, a number of HR tech startups appear to be thriving. Considered one of these corporations is small-business payroll supplier Gusto. The 14-year-old firm, final valued at over $9 billion, simply introduced that it surpassed $1 billion in income earlier this yr. Not like many startups that report annualized recurring income (ARR) — an estimate of the worth of their contracts within the upcoming 12 months — Gusto’s determine represents precise income earned over the earlier 12 months. What’s extra, the startup has been cash flow positive for a number of years.…